A substance in the toad poison, 5-MeO-DMT, can be dried into crystals and smoked in a pipe, producing an intense experience, A toad ceremony participant lying down after inhaling toad secretion smoke through a pipe, Toad ceremony participants dancing in Huntsville, Texas. The organizer of the event charges $250 for a ceremony, Brooke Tarrer, center, of the Universal Shamans of the New Tomorrow church, smoking a tobacco cigarette during preparation for a toad medicine ceremony, A ceremony participant after inhaling toad secretion smoke. A substance found in the toad toxins produces an intense experience generally lasting 15 to 30 minutes, The toxin, commonly called Five or Bufo, started to grip public attention in a big way over the past five years, Robert Villa, president of the Tucson Herpetological Society, said the surging demand for the Sonoran desert toad could lead its population to plummet, The toad is primarily found in the Sonoran desert in parts of the southwestern United States and northwestern Mexico, The toad has a remarkably long life span that can reach 20 years, A Sonoran desert toad is placed on its back, a position that calms it down, Exhaling smoke after taking venom through a pipe during the ceremony. Users often call the substance the “God molecule,” likening its use to a religious experience, A ceremony participant. The substance 5-MeO-DMT in the toad secretions remains effectively illegal in the United States, but law enforcement agencies are largely tolerating venom ceremonies. The substance is legal in Mexico, Before the ceremony, a cleansing with incense, A view in Tuscon, Ariz., where the toad hibernates underground most of the year and resurfaces to breed around the summer monsoon rains, The New Yorker, dot image pixel, dot image pixel, dot image pixel, Google, Man checking his blood-sugar levels. Diagram of how insulin resistance keeps glucose and insulin in the bloodstream. 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